16 Best Places to Stay on Route 66 (2023 Guide) – Trips To Discover

21c Museum Hotel – Oklahoma City, Oklahoma

The 21c Museum Hotel is fun and funky, just like Route 66, providing an ideal place to stay in Oklahoma City, a must-stop on the route. It’s home to Milk Bottle Grocery, a wedge-shaped building topped by a giant milk bottle that was created as an advertising gimmick in 1948. Route 66 Park, on the shores of Lake Overholser, celebrates the historic route while providing a great place for families with kids. At Route 66 Plaza, you’ll see an oversized map tracing the road course. Back at the hotel, take advantage of spa services to unwind after all that time in the car. It also includes a fabulous restaurant/lounge, a fitness center, and as the name belies, an art museum.